• Class: Dual GIP + GLP-1 Receptor Agonist with Niacinamide Support

• How it works: Tirzepatide activates both GLP-1 and GIP receptors to reduce appetite, regulate blood sugar, and support fat metabolism. The addition of Niacinamide (Vitamin B3) enhances absorption, may reduce injection site reactions, and provides added metabolic support.

• Typical dosing:

  • Starting dose: 2.5 mg weekly

  • Target dose: 5 mg – 15 mg weekly (gradual titration based on tolerance)

• Benefits of Niacinamide addition:

  • May improve bioavailability and consistency of response

  • Helps reduce the risk of skin irritation or injection site rash

  • Supports healthy lipid metabolism and insulin sensitivity

• Administration: Once-weekly subcutaneous injection, self-administered at home

• Cost: $299 dose up to 5mg/week

  $399 dose from 7.5mg to 12.5mg / week

  $499 dose of 15mg / week

• Available through Melt Medical via accredited compounding pharmacies

💡 This enhanced formulation may be ideal for individuals who want a customizable, convenient weight loss therapy with improved tolerability for sensitive skin.